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Infertility Has Been Traced to Plastics. A Warning for Humans?

August 08, 2018, 02:38:10 am suzytr says: Hello, any good churches in the Sacto, CA area, also looking in Reno NV, thanks in advance and God Bless you Smiley
January 29, 2018, 01:21:57 am Christian40 says: It will be interesting to see what happens this year Israel being 70 years as a modern nation may 14 2018
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September 24, 2017, 10:45:16 pm Psalm 51:17 says: The specific rule pertaining to the national anthem is found on pages A62-63 of the league rulebook. It states: “The National Anthem must be played prior to every NFL game, and all players must be on the sideline for the National Anthem. “During the National Anthem, players on the field and bench area should stand at attention, face the flag, hold helmets in their left hand, and refrain from talking. The home team should ensure that the American flag is in good condition. It should be pointed out to players and coaches that we continue to be judged by the public in this area of respect for the flag and our country. Failure to be on the field by the start of the National Anthem may result in discipline, such as fines, suspensions, and/or the forfeiture of draft choice(s) for violations of the above, including first offenses.”
September 20, 2017, 04:32:32 am Christian40 says: "The most popular Hepatitis B vaccine is nothing short of a witch’s brew including aluminum, formaldehyde, yeast, amino acids, and soy. Aluminum is a known neurotoxin that destroys cellular metabolism and function. Hundreds of studies link to the ravaging effects of aluminum. The other proteins and formaldehyde serve to activate the immune system and open up the blood-brain barrier. This is NOT a good thing."
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September 14, 2017, 04:31:26 am Christian40 says: i have thought that i'm reaping from past sins then my life has been impacted in ways from having non believers in my ancestry.
September 11, 2017, 06:59:33 am Psalm 51:17 says: The law of reaping and sowing. It's amazing how God's mercy and longsuffering has hovered over America so long. (ie, the infrastructure is very bad here b/c for many years, they were grossly underspent on. 1st Tim 6:10, the god of materialism has its roots firmly in the West) And remember once upon a time ago when shacking up b/w straight couples drew shock awe?

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Author Topic: Infertility Has Been Traced to Plastics. A Warning for Humans?  (Read 839 times)
Psalm 51:17
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« on: June 18, 2014, 07:17:37 pm »

Infertility in Spanish Pigs Has Been Traced to Plastics. A Warning for Humans?


A scientist has connected infertility in pigs to compounds in plastic bags.

A strange catastrophe struck Spain's pig farmers in the spring of 2010. On 41 farms across the country—each home to between 800 and 3,000 pigs—many sows suddenly ceased bearing young.

On some farms, all the sows stopped reproducing. On others, those that did become pregnant produced smaller litters.

When investigators examined the sows and the semen that had been used to artificially inseminate them—it had been collected from different boar studs and refrigerated—they couldn't find anything wrong. The sperm cells weren't misshapen. None of the sows were diseased. No microbes or fungal toxins were detected in their feed or water.

Only one factor was common to all the farms and studs: The plastic bags used for semen storage all came from the same place.

Investigating those bags has led Cristina Nerín, an analytical chemist at the University of Zaragoza who studies packaging materials, to publish new research that traces the pigs' infertility to chemical compounds in the plastics.

This is "the first time that the correlation between reproductive failures and compounds migrating from plastic materials [has been] studied and demonstrated," says Nerín, whose team published last month in the journal Scientific Reports.

The implications could extend far beyond the farm.

Some of the same chemicals found in the pigs' semen storage bags are routinely used in packaging food for humans and are known to migrate into food. The strange case of the Spanish pigs, Nerín says, "shows the real risks we face." (Explore an interactive showing toxic chemicals that may be lurking in your home.)

Not Just About Pigs

Cyclic lactone, for instance, is a common by-product in adhesives used in potato chip bags and sliced meat packages. It was one of the chemicals found in high levels in the semen bags that had been used on the farms with the highest rates of reproductive failure.

Another chemical found in high levels on those farms: a compound called BADGE, a derivative of the notorious bisphenol A (BPA). It's the building block of epoxy resins that form the basis for 95 percent of food and beverage can linings in the U.S. (Also see "Chemical BPA Linked to Heart Disease, Study Confirms.")

In one recent study led by analytical chemist Kurunthachalam Kannan of the New York State Department of Health in Albany, BADGE, which is also found in household dust, was detected in 100 percent of 127 urine samples collected from people in the U.S. and China.

BPA, the precursor of BADGE, is a known endocrine disruptor: It mimics and interferes with the action of a human hormone, in this case estrogen. A derivative of BADGE called BADGE-2H2O—which forms when BADGE meets water—is an even more potent estrogen mimic.

A lot of research—epidemiological, lab-animal, and clinical studies—has linked endocrine disruptors to adverse health effects, including abnormal testicular development, early puberty, prostate cancer, breast cancer, and even obesity.

Damaging DNA?

Nerín thinks the suspect chemicals in the pigs' bags came from adhesives used to glue together the multilayer plastic that made up the bags. But the chemicals in question aren't normally used for that purpose. Their presence in the Spanish pig semen bags may reflect some kind of unusual contamination.

The supplier of the bags, a company named Magapor, had contacted Nerín because of her expertise. "They were desperate," she says, "because they didn't find a reason why reproduction failed."

Nerín confirmed her suspicion that the high levels of cyclic lactone and BADGE were to blame by "spiking" a new batch of semen with a mix that included those two chemicals and inseminating two groups of 50 sows with either the spiked mixture or a control. Just 58 percent of the sows inseminated with the spiked semen became pregnant, compared with 84 percent of the controls.

Magapor had purchased the semen storage bags from a Chinese manufacturer. When the company switched to a different bag producer, the Spanish pigs' fertility returned to normal.

To complicate the story further, Nerín didn't find any evidence that BADGE was acting as an endocrine disruptor at the levels at which it was present in the semen bags. But lab experiments suggest BADGE is a mutagen as well as an endocrine disruptor: Besides binding to hormone receptors inside cells, it can bind to DNA, causing mutations.

Because the sperm cells in Nerín's pig study looked normal and moved and penetrated eggs normally, she believes many of the pregnancy failures may have resulted from damage to the sperm's DNA—which somehow caused fertilized embryos not to develop normally and not to implant in the sow's uterus.

Effects in Humans?

Meanwhile another paper published last month revealed a specific mechanism by which endocrine disruptors might indeed interfere with fertilization in humans.

One of the authors, physician Niels Skakkebaek of the Rigshospitalet, a university hospital in Copenhagen, has been studying testicular disorders and endocrine disruptors for decades. In a 1992 paper in the British Medical Journal, he reported evidence indicating that sperm quality had deteriorated among men in the United States and elsewhere over the previous 50 years.

In the new study, Skakkebaek; Timo Strünker of the Center of Advanced European Studies and Research in Bonn, Germany; and their colleagues exposed human sperm in lab tests to 96 common endocrine disruptors—chemicals, they write, that are "omnipresent in food, household, and personal care products."

They looked at the effects of the chemicals on a specific signaling conduit in sperm (and other cells) called a calcium channel. The calcium channel in sperm is usually activated by female hormones in the female reproductive tract, including progesterone released by cells surrounding the egg. Activation of the calcium channel allows calcium ions to flood into the sperm cells, which in turn affects their motion, causing them to swim toward an egg and penetrate it.

Skakkebaek and Strünker found that about one-third of the chemicals they tested in the lab evoked a "sizable" response by the calcium channel.

For example, some caused the sperm's tail to curl up rather than flick from side to side. The chemicals that had the strongest effects included ultraviolet light-filtering agents in sunscreens; plastic-softening phthalates used in food and drink containers; and fungicides and antibacterial compounds such as triclosan, which are commonly found in soaps, toothpaste, and toys.

"That was quite unexpected to find so many that could have an effect," Skakkebaek says. "This is the first time this has been shown."

If endocrine-disrupting chemicals are present in the female reproductive tract, Skakkebaek says, they may desensitize the sperm to signals from progesterone. "The sperm cells may have more difficulty in sensing where the egg is," he says. "They could also be swimming in the wrong direction, because they had wrong signals on the way."

That, in turn, might disrupt the process of fertilization.

Skakkebaek's lab tests, like the Spanish semen bags, placed the suspect chemicals in direct contact with sperm cells. But it's not known whether those chemicals are in fact present in the female reproductive tract in dangerous concentrations.

Some researchers question whether everyday exposure to such chemicals in food packaging, say, would have the same detrimental effects on sperm; after the chemicals were ingested, they would be metabolized in the human body, which could change their structure and toxicity.

One skeptic is Allan Pacey, a senior lecturer in andrology at the University of Sheffield in the U.K. He and his co-workers conducted two large epidemiological studies on thousands of British men, examining both occupational exposures to chemicals and lifestyle issues, such as drinking and smoking. They found that only two risk factors—exposure to glycol ether (a paint ingredient) and wearing tight underwear—were associated with "low motile sperm count."

"It is possible to measure effects on ejaculated sperm in the lab, but this is a long way removed from what may be happening in the real world,"  Pacey says.

Skakkebaek agrees that more studies of how chemical exposure affects actual humans are needed.

"Most of these chemicals are found in almost everybody," he says, referring to the ones in his recent study. "We know for sure that they are in our bodies, because we know for sure that they are excreted in our urine. But what we don't know for sure is the concentration."

As for Nerín's study of the Spanish pigs, "they really found a clear association" between chemical exposure and infertility, Skakkebaek says. "I believe it should be taken as a warning."
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« Reply #1 on: June 18, 2015, 01:36:24 pm »

Low male fertility caused by sunscreen, everyday plastics – scientist

Low fertility rates have been blamed on everything from laptops to cycling – but a scientist now claims that other common items are also diminishing men's chances of fatherhood. From sunscreen to frying pans, he says men aren't as safe as they thought.

According to Danish researcher Niels Jorgensen, certain chemicals are responsible for low fertility rates – and those chemicals are found all around us.

“Modern life is having an impact because we are exposed to so many chemicals and we don’t know what they do,” said Jorgensen, a consultant at the Department of Growth and Reproduction at Rigshospitalet in Copenhagen, as quoted by The Times.

Jorgensen's remarks follow the scientist's 15-year study of almost 5,000 Danish men, with an average age of 19.

He found that only 25 percent had “really good semen quality – that is shape and concentration of sperm."

Meanwhile, about 15 percent had very poor quality of sperm. “You would predict they would need some kind of fertility treatment to become fathers,” he said. A further 27 percent could expect a prolonged wait to father children.

Jorgensen made his remarks at the European Society of Human Reproduction and Embryology’s annual conference in Lisbon this week.

The chemicals of concern are known as phthalates, and they're found in everything from shower curtains to car dashboards and cleaning materials – products that most men come into contact with on a daily basis.

Jorgensen also believes PFCs are “extremely harmful.” These are found in everyday items such as non-stick pans and waterproof jackets.

While throwing away a particular coat or upgrading to a different frying pan may not seem too drastic, Jorgensen did have a more controversial suggestion – abandoning the use of sunscreen.

“We are advised to protect ourselves with these sunblocks but it seems when you go to the laboratory and test some of these chemicals they can interfere with the sperm function,” Jorgensen said.

“If I was to advise my own family, I would say don’t use it,” he added.

But it's not just grown men that are at risk from the allegedly dangerous substances – unborn boys are thought to be particularly in danger.

This has led Jorgensen to also advise against the use of sunscreen and make-up for pregnant women, as those substances could negatively impact the future sperm production of male fetuses.

But Jorgensen's suggestion of ditching sunscreen has been criticized by Dr. Chris Flower of the UK's Cosmetics, Toiletry and Perfumery Association – an organization that lobbies for companies involved in the making, supplying, and selling of cosmetic and personal care products.

"We can state categorically that cosmetic products are required by strict European laws to be safe. Not to wear sun screen is an outrageous piece of advice because we know the risks of sun damage, and to suggest that not using sun protection products is a good idea is a terrible thing to do,” he said.
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« Reply #2 on: October 25, 2016, 04:47:19 am »

It can also cause depression and memory impairment

Plasticizers, known as a chemical called phthalates, are found in a variety of household products.

However, recent studies show that this dangerous chemical is found in pizza takeaway boxes and other fast food containers, meaning many people are ingesting it without being aware of its very serious side effects.

A recent study examined 9,000 people. It was found that those who ate fast food and take-out more often had higher levels of  phthalates found in their urine than those who did not frequently eat fast food. It was theorized that PVC tubing, plastic gloves the food handlers use and the containers the food comes in were the likely culprits of this build up of the chemical.

It was also observed that those who had a higher amount of the chemical in their body consumed more meat and grains than those who did not.

Phthalates are found in many plastic household items, which help keep plastic flexible. But they were found to be likely carcinogenic and the U.S. Product Safety Commission banned them in children’s toys.

But if this chemical abounds, what is so dangerous about it?

When this plasticizer is found in wildlife refuges, it is often linked to the feminization of non-intersex male animals who then go on to develop female characteristics. Although no studies have been done on humans to determine if this is also the case, researchers say the results are relevant as humans have similar endocrine systems.

Additionally, exposure to the chemical while pregnant can lead to the masculinization of a baby, as well as disrupting the thyroid levels of the fetus in the crucial third trimester.
Researchers have also found that pregnant women exposed to the chemical have an over 72%  chance of having a child who would later develop asthma between the ages of 5 and 11.

The chemical can also lead to migraines, depression and impaired memory in senior adults.

In order to protect yourself from phthalates, it is recommended that you cut back on your take-out and fast food. It is also recommended that you replace plastic products in your household with glass or fabric alternatives and that you avoid purchasing food with any plastic wrapping.

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